Association between the Angiotensinogen (AGT) gene (M235T) polymorphism and Essential Hypertension in Egyptian patients
نویسندگان
چکیده
منابع مشابه
Association between G-217A polymorphism in the AGT gene and essential hypertension: a meta-analysis.
Numerous studies have evaluated the association between the angiotensinogen (AGT) G-217A gene polymorphism and essential hypertension risk. However, the results have been inconsistent. We examined whether the AGT G-217A gene polymorphism confers essential hypertension risk by conducting a meta-analysis. We conducted a literature search of the Google Scholar, PubMed, and China National Knowledge...
متن کاملT+31C polymorphism of angiotensinogen gene and essential hypertension.
A common variant at codon 235 of the angiotensinogen gene with methionine to threonine amino acid substitution (AGT M235T) has been reported as a genetic risk for essential hypertension. However, the frequency of AGT T235 was heterogeneous among races, and a positive association between AGT M235T and hypertension was not settled. To examine the association in a general population of Japanese (n...
متن کاملGender-specific association of M235T polymorphism in angiotensinogen gene and diabetic nephropathy in NIDDM.
This study examined the association between the development of nephropathy in non-insulin-dependent diabetes mellitus (NIDDM) patients and M235T polymorphism in the angiotensinogen gene. White NIDDM patients with diabetic nephropathy (case subjects, n = 117) and patients without any evidence of nephropathy and > or = 10 years of NIDDM (control subjects, n = 125) were selected from among patient...
متن کاملT131C Polymorphism of Angiotensinogen Gene and Essential Hypertension
A common variant at codon 235 of the angiotensinogen gene with methionine to threonine amino acid substitution (AGT M235T) has been reported as a genetic risk for essential hypertension. However, the frequency of AGT T235 was heterogeneous among races, and a positive association between AGT M235T and hypertension was not settled. To examine the association in a general population of Japanese (n...
متن کاملMeta-analysis of the association of 4 angiotensinogen polymorphisms with essential hypertension: a role beyond M235T?
Angiotensinogen (AGT) gene polymorphisms have been linked to increased risk of hypertension, but the data remain controversial. In this study we review the most commonly investigated polymorphisms at the AGT locus (other than M235T) and provide summary estimates regarding their association with essential hypertension, while addressing heterogeneity, as well as publication biases. Data on 26 818...
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ژورنال
عنوان ژورنال: The Egyptian Heart Journal
سال: 2015
ISSN: 1110-2608
DOI: 10.1016/j.ehj.2013.10.001